The Two Distinct Phases of Inflammatory Response in the Dog’s Knee Joint

  • C. G. Van Arman
  • R. P. Carlson
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 8)


The inflammations caused by various agents may be quite different from each other in the details of the mechanisms involved, even though the gross features of the swelling, redness and pain may not be ostensibly different. In this chapter we will demonstrate some differences among agents and will attempt to explain them to some extent. The agents used were bradykinin, serotonin, Hageman factor, ellagic acid, carrageenan, sodium urate, and cellulose sulfate. The findings permit us to set up certain hypotheses about the general nature of the acute inflammatory reaction, particularly the role of the neutrophil.


Synovial Fluid Ellagic Acid Soybean Trypsin Inhibitor Acute Inflammatory Reaction Cellulose Sulfate 
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Copyright information

© Plenum Press, New York 1970

Authors and Affiliations

  • C. G. Van Arman
    • 1
  • R. P. Carlson
    • 1
  1. 1.Merck Institute for Therapeutic ResearchWest PointUSA

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