Histamine, Bradykinin and Serotonin Potentiation by the Slow Reacting Substance in Anaphylaxis
The formation of smooth muscle stimulating substance which causes slow and long-lasting contraction of the guinea-pig ileum, has been found in some animal species and several tissues (Brocklehurst 1960, Rapp 1961, Uvnas 1963). The substance is an unsaturated hydroxylated myotropic fatty acid. Its chemical nature is, however, still unknown.
KeywordsAnaphylactic Reaction Graphic Purification Slow React Substance Bronchial Spasm Maximal Potentiation
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