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Investigation of Pharmacological Agents Released in Human Cutaneous Inflammation Using a Direct Perfusion Method

  • Malcolm W. Greaves
  • Jørgen Søndergaard
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 8)

Abstract

Despite the voluminous literature on naturally occurring vasoactive agents the problem of mediators of inflammation in man remains unsolved. Bradykinin, serotonin (5-hydroxytryptamine) and histamine are known to be highly potent in producing inflammation in human skin (Greaves and Shuster, 1968). However, direct evidence that these agents play any part in human inflammation is lacking.

Keywords

Vasoactive Agent Kinin Activity Mercury Vapour Lamp Urticaria Pigmentosa Flexor Aspect 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. FOX, R.H. & HILTON, S.M.(1958). J. Physiol. 142, 219–232.PubMedGoogle Scholar
  2. GREAVES, M.W. & SHUSTER, S. (1968). J.Physiol. 193, 255–267.Google Scholar
  3. GREAVES, M.W. & SONDERGAARD, J. (1969). Arch.Derm, (in press).Google Scholar
  4. LOGAN, G. & WILHELM, D.L. (1966). Brit. J. Exptl. Pathol. 47, 300–314.Google Scholar
  5. WILHELM, D.L. (1965). In “The Inflammatory Process” (B.W. Zweifach, L. Grant and R.T. McCluskey, ed.). pp.389–425, Academic Press, London.Google Scholar

Copyright information

© Plenum Press, New York 1970

Authors and Affiliations

  • Malcolm W. Greaves
    • 1
  • Jørgen Søndergaard
    • 1
  1. 1.University Department of DermatologyNewcastle-upon-TyneEngland

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