Plasma Kinin Formation in Rheumatoid Arthritis

  • C. A. Keele
  • V. Eisen
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 8)


Synovial exudates in various forms of arthritis contain plasma kinin-forming enzymes and substrates in concentrations which may approach those found in plasma (Armstrong et al., 1957; Eisen, 1966; Jasani et al., 1967). Spontaneous kinin formation was observed by Melchiorri (1963). Melmon et al. (1967) found kinin equivalent to bradykinin 3–44 ng/ml. in six out of six exudates from rheumatoid joints.


Rheumatoid Factor Kinin Level Rheumatoid Patient Rheumatoid Joint Synovial Effusion 
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Copyright information

© Plenum Press, New York 1970

Authors and Affiliations

  • C. A. Keele
    • 1
  • V. Eisen
    • 1
  1. 1.Rheumatology Research DepartmentMiddlesex Hospital Medical SchoolLondon, W.1UK

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