Biochemistry of Kinin-Releasing Enzymes in the Venom of the Viper Bitis Gabonica and of the Lizard Heloderma Suspectum

  • Dietrich Mebs
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 8)


Since the investigations of Rocha e Silva et al. (1949) on Bothrops jararaca venom and of Deutsch and Diniz (1955) on other Crotalidae venoms, it is known, that snake venoms possess kinin-releasing properties. Suzuki et al. (1966) purified a bradykinin-releasing enzyme from the venom of Agkistrodon halys blomhoffii and recently Cohen et al. (1969) from Echis coloratus venom.


Snake Venom Venom Gland Heloderma Suspectum King Cobra Esterolytic Activity 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Cohen, I., M. Zur, E. Kaminsky and Vries, Toxicon 7, 3 (1969)PubMedCrossRefGoogle Scholar
  2. Deutsch, H.F. and C.R. Diniz, J.biol.Chem. 216, 17 (1955)PubMedGoogle Scholar
  3. Ekfors, T.O., P.J. Riekkinen, T. Malmiharju and V.K. Hopsu-Havu, Hoppe-Seyler’s Z.physiol.Chem. 348, 111 (1967)PubMedCrossRefGoogle Scholar
  4. Habermann, E., Hoppe-Seyler’s Z.physiol.Chem. 328, 15 (1962)PubMedCrossRefGoogle Scholar
  5. Habermann, E. and W. Klett, Biochem. Z. 346, 133 (1966)PubMedGoogle Scholar
  6. Iwanaga, S., T. Sato, Y. Mizushima and T. Suzuki, J.Biochem. (Tokyo) 58, 123 (1965)Google Scholar
  7. Mebs, D. and H.W. Raudonat, Memorias do Instituto Butantan (São Paulo), 33, 907 (1966)Google Scholar
  8. Mebs, D. and H.W. Raudonat, Naturwissenschaften 54, 494 (1967)PubMedCrossRefGoogle Scholar
  9. Mebs, D., Hoppe-Seylerś Z.physiol.Chem. 350 (1969)Google Scholar
  10. Riekkinen, P.J., T.O. Ekfors and V.K. Hopsu, Biochim. biophys. Acta, 118, 604 (1960)Google Scholar
  11. Rocha e Silva, M., W.T. Beraldo and G. Rosenfeld, Amer.J. Physiol. 156, 261 (1949)Google Scholar
  12. Suzuki, T., S. Iwanaga, Y. Mizushima and T. Sato, in “Hypotensive peptides” p.149, Springer Verlag (1966)CrossRefGoogle Scholar
  13. Werle, E. and B. Kaufmann-Boetsch, Naturwissenschaften 46, 559 (1959)CrossRefGoogle Scholar
  14. Whitaker, J.P., Analytic.Chem. 35, 1950 (1963)CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1970

Authors and Affiliations

  • Dietrich Mebs
    • 1
  1. 1.Institut für gerichtliche und soziale MedizinUniversität Frankfurt a.M.Germany

Personalised recommendations