Depence of Oxyhemoglobin Dissociation and Intraery-Throcytic 2,3-DPG on Acid-Base Status of Blood. II. Clinical and Experimental Studies

  • P. Astrup
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 6)


Since our first report (Astrup, 1969) at a symposium in Uppsala in February 1969 on changes of the oxygen affinity of hemoglobin due to pH-dependent 2,3-DPG changes we have studied this relationship more extensively in patients with acid-base disorders and also in normal individuals with induced changes of the acid-base status of the blood. The results of these investigations will be presented in this paper.


Metabolic Alkalosis Oxygen Affinity Feedback Control System Nium Chloride Standard Bicarbonate 
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Copyright information

© Plenum Press, New York 1970

Authors and Affiliations

  • P. Astrup
    • 1
  1. 1.RigshospitaletCopenhagenDenmark

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