Abstract
In a previous communication the appearance of an aleukemic malignant lymphoma resembling Burkitt’s tumor in Swiss mice was described [1]. The lymphoma was observed much more frequently in mice immune toPlasmodium berghei than in controls of the same age. By electron microscopy, virus particles could be shown in the germinal centers of the splenic lymphatic nodules during the very early stages of malignant growth. The thymus was seen to be even more involved than the spleen (64% as opposed to 44%). Since in most instances the thymus shows distinct changes during primary infection [2, 3], the question arises as to whether the thymus can be regarded as a focus of tumor development.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
C. Jerusalem, Z. Tropenmed. Parasitol., 19:94, 1968.
C. Jerusalem, Ann. Soc. Beige Med. Trop., 45:405, 1965.
W. Eling and C. Jerusalem, Anat. Anz., 121:197, 1968.
E. R. Fisher, in: R. A. Good and Ann E. Gabrielsen, Eds., The Thymus in Immunobiology, p. 676. New York-Evanston-London: Harper and Row, 1964.
D. Metcalf, The Thymus: Its Role in Immune Response, Leukemia Development and Carcinogenesis. Berlin-Heidelberg-New York: Springer-Verlag, 1966.
U. Bernhard, in: A. V. S. Reuck and J. Knight, Eds., Cellular Injury, p. 209. London: J. h A. Churchill, 1964.
W. Kretschmar and C. Jerusalem, Z. Tropenmed. Parasitol., 14:279, 1963.
C. Jerusalem, Z. Tropenmed. Parasitol., 15:371, 1964.
E. De Harven, Discussion on paper by Furth et al., in: R. A. Good and Ann E. Gabrielsen, Eds., The Thymus in Immunobiology, p. 621. New York-Evanston-London: Harper and Row, 1964.
D. W. van Bekkum, in: Biotechnisch Symposium L.W.L., pp. 7–12. Utrecht: Transitorium, 1965.
C. Jerusalem and Ute Heinen, Anat. Anz., 120:157, 1967.
D. P. Burkitt, 9th Ann. Meeting Brit. Ass. Cane. Res., London, 1968.
L. Dmochowski, C. E. Grey, and L. Gross, in: Radiation Biology and Cancer, Symposium on Fundamental Cancer Research, p. 382. University of Texas Press, 1958.
I. Furth, H. Okano, and A. Kunil, in: R. A. Good and Ann E. Gabrielsen, Eds., The Thymus in Immunobiology, p. 595. New York-Evanston-London: Harper and Row, 1964.
G. J. V. Nossal, Ann. N. Y. Acad. Sci., 120:170, 1964.
J. F. A. P. Miller, Brit. Med. Bull., 21:111, 1965.
M. Galton and Penelope B. Reed, Transplantation, 4:168, 1966.
L. Dmochowski, F. Padgett, and L. Gross, Cancer Res., 24:869, 1964.
E. A. Gall and H. Rappaport, in: Proceedings of the Twenty- third Seminar of the American Society of Clinical Pathologists, October 4, 1957.
G. T. O’Conor, Cancer Philad., 14:270, 1961.
G. T. O’Conor, H. Rappaport, and E. B. Smith, Cancer Philad. 18:411, 1965.
G. J. V. Swaen, J. Natl. Cancer Inst., 36:1027, 1966.
E. De Harven, in: A. J. Dalton and F. Haguenau, Eds., Tumors Induced by Viruses: U1trastructural Studies, p. 183. New York and London: Academic Press, 1962.
L. Dmochowski, in: F. O. J. Hayhoe, Ed., Current Research in Leukemia. Cambridge: University Press, 1965. 111.4
J. J. Butler, A. Szakas, and J. G. Sincovics, Am. J. Pathol., 51:629, 1967.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1969 Plenum Press
About this chapter
Cite this chapter
Jerusalem, C. (1969). Thymic Germinal Centers as Foci of a Lymphoma Resembling Burkitt’s Tumor. In: Fiore-Donati, L., Hanna, M.G. (eds) Lymphatic Tissue and Germinal Centers in Immune Response. Advances in Experimental Medicine and Biology, vol 5. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3192-6_52
Download citation
DOI: https://doi.org/10.1007/978-1-4684-3192-6_52
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-3194-0
Online ISBN: 978-1-4684-3192-6
eBook Packages: Springer Book Archive