The Morphologic Sites of Bacteriolytic Antibody Formation to E. Coli Antigen in Mice

  • J. Allen
  • I. Young
  • H. Friedman
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 5)


The presence of immunoglobulins and antibody in cells associated with germinal centers of lymphoid follicles has been demonstrated by a number of investigators during the past few years [1, 2, 3, 4, 5, 6, 7, 8]. The distribution of antibody-containing cells in such follicles seems to follow a characteristic pattern. In addition, a number of investigators have indicated that antigen may be “trapped” in lymphoid follicles and associated germinal centers [9, 10, 11, 12, 13].


Germinal Center Lymphoid Follicle Sheep Erythrocyte Antibody Activity Brain Heart Infusion Agar 
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Copyright information

© Plenum Press 1969

Authors and Affiliations

  • J. Allen
    • 1
  • I. Young
    • 1
  • H. Friedman
    • 1
  1. 1.Departments of Microbiology and Pathology, Division of LaboratoriesAlbert Einstein Medical CenterPhiladelphiaUSA

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