Kinetic Studies on the Induction of Immune Tolerance to Protein Antigen in Sublethally X-Irradiated Rabbits
Immune tolerance is a phenomenon resulting from the interaction of antigen with cells of the immune mechanism under conditions that are far from being understood. The original assumption as formulated by Medawar  and Dresser  suggests that tolerance is the outcome of antigen interplay with immature target cells. With the accumulation of quantitative data it was later suggested that tolerance may result from the “overloading” of a small number of competent cells with a relatively large amount of antigen.
KeywordsHuman Serum Albumin Immune Tolerance Protein Antigen Tolerance Induction Immune Recovery
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