Blood-Brain Barrier: Techniques for the Intracerebral Administration of Drugs

Part of the Handbook of Psychopharmacology book series (HBKPS, volume 2)


The greatest concern of the psychopharmacologist whose wish is to elucidate the properties of a given compound is its mode of action when administered by the systemic route. The basis for this is elementary. A drug that is prescribed to a patient ordinarily is taken orally or parenterally. For this reason, the vast majority of the research done on compounds that affect the central nervous system has utilized one or more of the systemic methods of administration. This having been said, there are five reasons why the logistics of this approach is not entirely coherent from a purely experimental—not clinical—standpoint.


Lateral Ventricle Cocoa Butter Evans Blue Cerebral Ventricle Ventricular Lumen 
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Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  1. 1.Laboratory of NeuropsychologyPurdue UniversityLafayetteUSA

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