Skip to main content

Functional Interrelationships of Principal Catecholaminergic Centers in the Brain

  • Chapter
Catecholamines and Behavior · 1

Abstract

The central nervous system is truly remarkable in its ability to maintain stable normal function amidst myriad environmental factors which tend to disrupt its equilibrium. It maintains its functional balance by means of adaptive mechanisms. During the normal course of existence external forces act on the organism, altering its internal environment so that important elements fall outside their range of optimal functioning. Exceeding the optimal range activates specialized adaptive mechanisms which tend to restore the internal environment to the optimal state. Thus, the initial change acts as a stimulus to processes which tend to reverse that change. This regulatory pattern of action and reaction is ineffective only when the initial change is so extreme as to be irreversible or when the mechanisms to counter the initial change are either weakened or absent.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Ansell, G. B., Beeson, M. F., Bradley, P. B., 1969, The effects of stressful, stimuli and drugs of the concentrations and turnover rates of monoamine in rat brain, in: The Present Status of Psychotropic Drugs, pp. 299–301, Proc. CINP VI Intern. Congr. ( Tarragone, 1968 ).

    Google Scholar 

  • Barbeau, A., Murphy, C. F. and Sourkes, T. L., 1961, Excretion of dopamine in diseases of basal ganglia. Science 133: 1706.

    Article  PubMed  CAS  Google Scholar 

  • Barbeau, A., Tétreault, L., Oliva, L., Morazain, L., and Gardin, L., 1966, Pharmacology of akinesia. Investigations on 3,4-dimethoxy-phenylethylamine, Nature (London) 209: 719.

    Article  CAS  Google Scholar 

  • Bechtereva, N. P., 1971, The Neurophysiological Base of the Mental Activity in Man,Leningrad.

    Google Scholar 

  • Bechtereva, N. P., Grigorovitch, K. A., and Zontov, V. V., 1963, On the pathogenesis and the therapy of the Raynaud disease, Zh. Nevropatol. i Psikhiatr. 5: 641.

    Google Scholar 

  • Bechtereva, N. P., Bondartchuk, A. N., and Zontov, V. V., 1965, The Raynaud’s Disease,Leningrad.

    Google Scholar 

  • Bechtereva, N. P., Bondartchuk, A. N., and Smirnov, V. M., Trochatchev A. I., 1967, The Physiology and the Pathophysiology of the Deep Brain Structures in Man,Leningrad-Moskva.

    Google Scholar 

  • Bechtereva, N. P., Kambarova, D. K., and Matveev, Yu.K., 1970, The functional characteristic of the links of the cerebral control systems for mental and motor functions in man, Fiziol. Zh. SSSR 56: 1081.

    Google Scholar 

  • Bertler, A., 1964, Dopamine in the central nervous system, in: Biochemical and Neurophysiological Correlations of Centrally Acting Drugs ( E. Trabucchi, R. Paoletti, and N. Canal. eds.), pp. 51–55, Pergamon Press, New York.

    Google Scholar 

  • Carlsson, A., 1959, The occurrence, distribution and physiological role of catecholamines in the nervous system, Pharmacol. Rev. 11: 490.

    PubMed  CAS  Google Scholar 

  • Carlsson, A., 1972, Biochemical and pharmacological aspects of parkinsonism, Acta Neurologica Scand. 48: 11.

    Article  CAS  Google Scholar 

  • Connor, J. D., 1970, Caudate nucleus neurones: correlation of the effects of substantia nigra stimulation with iontophoretic dopamine, J. Physiol. 208 (3): 323.

    Google Scholar 

  • Ehringer, H., and Hornykiewicz, O., 1960, Verteilung von Noradrenalin und Dopamin (3Hydroxytyramin) im Gehirn des Menschen und ihr Verhalten bei Erkrankungen des extrapyramidalen Systems, Klin. Wochschr. 38: 1236.

    Article  CAS  Google Scholar 

  • Everett, G. M., Borcherding, J. W., 1970, L-dopa: effect on concentrations of dopamine, nor-epinephrine, and serotonin in brains of mice, Science 168: 84Q

    Article  Google Scholar 

  • Fanchaps, A., Daepfner, N., Weidmann, H., and Cerletti, A., 1960, Pharmakologische Charakterizierung von Deseril, einem Serotonin-Antagonisten, Schweiz. Med. Wochschr. 90: 1040.

    Google Scholar 

  • Feltz, P., 1970, Relation nigrostriatale: essai de différenciation des excitatins et inhibitions par micro-iontophorèse de dopamine, J. Physiol. Suppl. 62 (1): 151.

    Google Scholar 

  • Freedman, D. X., 1961, Effect of LSD-25 on brain serotonin, J. Pharmacol. Exptl. Therap. 134: 160.

    CAS  Google Scholar 

  • Friedhoff, A. J., Hekimian, L., Alpert, M., and Tobach, E., 1963, DIhydroxyphenylalanine in extrapyramidial diseases, J. Am. Med. Assoc. 184: 285.

    Article  CAS  Google Scholar 

  • Friedhoff, A. J., Hekimian, L., Alpert, M., and Tobach, E., 1963, DIhydroxyphenylalanine in extrapyramidial diseases, J. Am. Med. Assoc. 184: 285.

    Article  CAS  Google Scholar 

  • Friedhoff, A. J., Hekimian, L., Alpert, M., and Tobach, E., 1963, DIhydroxyphenylalanine in extrapyramidial diseases, J. Am. Med. Assoc. 184: 285.

    Article  CAS  Google Scholar 

  • Granerus, Ann-Katherine, Jagenburg, Rudolf, Stig, Rödjer and Alvar, Svanborg, 1971, Inhibition of L-phenylalanine absorption by L-dopa in patients with parkinsonism, Proc. Soc. Exptl. Biol. Med. 137, 3: 942.

    Google Scholar 

  • Hornykiewicz, 0., 1964, The role of dopamine (3-hydroxytyramine) in parkinsonism, in: Biochemical and Neurophysiological Correlations of Centrally Acting Drugs, ( E. Trabucchi, R. Paoletti and N. Canal, eds.), pp. 57–68, Pergamon Press, New York.

    Google Scholar 

  • Hornykiewicz, 0., 1966, Dopamine (3-hydroxytyramine) and brain function, Pharmacol. Rev. 18: 925.

    Google Scholar 

  • Hull, C. D., Bernardi, G., and Buchwald, N. A., 1970, Intracellular responses of caudate neurons to brain stem stimulation, Brain Res. 22: 163.

    Article  PubMed  CAS  Google Scholar 

  • Iliukhina, V. A., 1972, The slow electrical processes in the human brain during mental and motor activity (with regard to the conditions of the central biochemical mediation), A vtoref. Kand. Diss., Leningrad.

    Google Scholar 

  • Kambarova, D. K., 1967, The central mechanisms of the paroxysmal diseases of non-epileptic kind. Avtoref. Kand. Diss., Leningrad.

    Google Scholar 

  • Kaminsky, L. S., 1959, Processing of the Clinical and Laboratory Data,Moskva. Kaminsky, L. S., 1964, Statistical Processing of the Clinical and Laboratory Data,Moskva.

    Google Scholar 

  • Kostowski, W., and Giacalone, E., 1969, Stimulation of various forebrain structures and brain 5HT, 5HIAA and behaviour in rats, in: The Present Status of Psychotropic Drugs, pp. 289–291 Proc. CINP. VI. Intern. Cong. ( Tarragone, 1968 ).

    Google Scholar 

  • Kostowski, W., and Giacalone, E., 1969, Stimulation of various forebrain structures and brain 5HT, 5HIAA and behaviour in rats, in: The Present Status of Psychotropic Drugs, pp. 289–291 Proc. CINP. VI. Intern. Cong. ( Tarragone, 1968 ).

    Google Scholar 

  • Matlina, E. Sh., and Menshikov, V. V., 1967, The Clinical Biochemistry of the Catecholamines, pp. 113–127, Moskva.

    Google Scholar 

  • Misyuk, N. S., Prigun, P. P., Korenevskaia, A. A., and Misyuk, E. M., 1965, The Data on the Serotonin Metabolism Under Inhibitory Condition of Brain, Minsk.

    Google Scholar 

  • Smirnov, V. M., 1967, In: The Localization Problems in Psychoneurology, Vol. X, pp. 22–48, ( Tr. in-st im. Bechtereva ), Leningrad.

    Google Scholar 

  • Udenfriend, S., Titus, E., and Weissbach, H., 1955, The identification of 5-hydroxy-3-indoleacetic acid in normal urine and a method for its assay, J. Biol. Chem. 216: 499.

    PubMed  CAS  Google Scholar 

  • Verzeano, M., 1972, Pacemakers, synchronization and epilepsy, in: Synchronization of EEG Activity in Epilepsies ( H. Petsche and M. A. B. Brazier, eds.), pp. 155–188, Springer-Verlag, Wien, New York.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1975 Plenum Press, New York

About this chapter

Cite this chapter

Bechtereva, N.P., Kambarova, D.K., Pozdeev, V.K. (1975). Functional Interrelationships of Principal Catecholaminergic Centers in the Brain. In: Friedhoff, A.J. (eds) Catecholamines and Behavior · 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3135-3_5

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-3135-3_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3137-7

  • Online ISBN: 978-1-4684-3135-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics