Long Term Treatment with the Combination SMZ/TMP in Children with Urinary Tract Infections

  • Leon Bernstein Hahn
  • Carlos A. Barclay
Part of the Chemotherapy book series (CT, volume 6)


The results of a long-term treatment of 34 children with chronic urinary tract infections, with the combination SMZ/TMP were reported. Twenty-six were females and 8 males and they all had congenital urinary tract obstructions or anomalies. Eight out of them underwent over a year’s treatment; the other 26 between one and twelve months. The dosage schedule was 20 mg per Kg SMZ and 5 mg Kg TMP twice daily. 67.5% remained with sterile urine cultures; 17.7% developed re-infections and 14.8% recurrences. General tolerance was excellent and the authors point out the absence of deterioration or impairment in renal function tests.


Urinary Tract Infection Urine Culture Kidney Function Test Quarterly Period Chronic Urinary Tract Infection 
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Copyright information

© Springer Science+Business Media New York 1976

Authors and Affiliations

  • Leon Bernstein Hahn
    • 1
  • Carlos A. Barclay
    • 1
  1. 1.Instituto Nacional de Rehabilitacion del Lisiado ServicioUrologia y Departamento de Investigaciones ClinicasBuenos AiresArgentina

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