The Concentration of Sulphamethoxazole and Trimethoprim in Human Prostate Gland

  • W. Oosterlinck
  • R. Defoort
  • G. Renders
Part of the Chemotherapy book series (CT, volume 6)


Sulphamethoxazole and trimethoprim concentrations were measured in 19 enucleated human prostate glands. For sulphamethoxazole the ratio plasma concentration to that of the prostate varied from 1.25 to 3.29. The trimethoprim concentrations were 2 to 3 times higher than in the plasma. These results are compared with the data of the literature. It seems obvious that the association SMZ-TMP is very useful in the treatment of chronic bacterial prostatitis.


Prostate Gland Nalidixic Acid Chronic Prostatitis Benign Prostate Hypertrophy Chronic Bacterial Prostatitis 
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Copyright information

© Springer Science+Business Media New York 1976

Authors and Affiliations

  • W. Oosterlinck
    • 1
  • R. Defoort
    • 1
  • G. Renders
    • 1
  1. 1.Department of UrologyAkademisch ZiekenhuisGhentBelgium

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