Miconazole Plasma Levels in Healthy Subjects and in Patients with Impaired Renal Function
Systemic mycoses are increasingly recognized in association with various clinical situations. The paucity and toxicity of available drugs and drug resistance of yeasts all contribute to making the treatment of these infections problematic. It is therefore essential to have new, potentially useful antifungal drugs thoroughly explored. One of these, miconazole, an imidazole-derivate, has been shown to have potent fungistatic activity and few side-effects (Brugmans et al., 1972).
KeywordsTotal Radioactivity Systemic Mycosis Oral Adminis Group Band Single Intravenous Infusion
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