Review of Imidazole Group

  • R. J. Holt
Part of the Chemotherapy book series (CT, volume 6)


Early indication of the antimicrobial potential of the imidazoles was given by Woolley (1944) in his report that benzimidazole and certain of its derivatives inhibited the growth of some fungi and bacteria. Woolley had noticed the close structural resemblance between benzimidazole and the purines and he showed that the inhibition of microbial growth was reversed by the aminopurines adenine and guanine, although other purines were ineffective.


Systemic Mycosis Imidazole Derivative Tinea Pedis Imidazole Group Vaginal Candidiasis 
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Copyright information

© Springer Science+Business Media New York 1976

Authors and Affiliations

  • R. J. Holt
    • 1
  1. 1.Department of Clinical MicrobiologyQueen Mary’s Hospital for ChildrenCarshaltonUSA

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