The Efficiency of Metronidazole ‘Flagyl’* Against Trypanosoma Evansi in vivo

  • A. M. Mandour
  • A. M. Abd-El Rahman
Part of the Chemotherapy book series (CT, volume 6)


Trypanosoma evansi is the cause of an important disease in camels known as Surra. This parasite might also be the cause of an acute and fatal disease in horses and dogs, while the infection results in a chronic disease in donkeys and transient in cattle. (Levine, 1961). According to Chandler and Read (1961) animals were formerly treated, with only fair success, with antimony compounds and antrypol, but recently two new drugs, dimidium bromide (Phenanthridium) and antrycide in the form of methyl sulphate or chloride salts, have greatly brightened the picture. However, antrycide is less effective against Trypanosoma brucei. T.evansi and T. equiperdum. On the other hand, dimidium bromide is ineffective against T.brucei, T.evansi and T.simiae.


Blood Film Chloride Salt Blood Stage Entamoeba Histolytica Trypanosoma Brucei 
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Copyright information

© Springer Science+Business Media New York 1976

Authors and Affiliations

  • A. M. Mandour
    • 1
  • A. M. Abd-El Rahman
    • 1
  1. 1.Department of Parasitology, Faculty of MedicineAssiut UniversityEgypt

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