A Rural Study in Tanzania of the Chemosuppressant Activity of Various Regimes of Co-trimoxazole or Chloroquine in Subjects with P.falciparum Parasitaemia

  • Th. J. Goosen
  • M. A. L. Goosen
  • A. J. Salter
Part of the Chemotherapy book series (CT, volume 6)

Abstract

Efficacy of co-trimoxazole against a wide range of bacterial infections is beyond dispute. Both components of this combination interfere at two sequential points in the folate biosynthetic pathway of bacteria and Plasmodia.

Keywords

Transportation Folate Malaria Chloro Malaria Parasite 

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References

  1. 1.
    Haworth, J, Personal communication.Google Scholar
  2. 2.
    Hackett, L.W. (1944), J. nat. Malar. Soc., 3, 121.Google Scholar

Copyright information

© Springer Science+Business Media New York 1976

Authors and Affiliations

  • Th. J. Goosen
    • 1
  • M. A. L. Goosen
    • 1
  • A. J. Salter
    • 2
  1. 1.East African Institute of Malaria and Vector-borne DiseasesAmaniTanzania
  2. 2.Department of Clinical InvestigationWellcome Foundation Ltd.LondonUK

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