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Interactions of New Cephalosporins with Some Cephalosporinases

  • Roger Labia
Part of the Chemotherapy book series (CT, volume 5)

Abstract

Bacterial strains resistant to one, or few, ß lactam antibiotics generally produce ß lactamases which are the enzymes able to cleave an amide bond in penicillins and cephalosporins and make the penicilloic thus obtained completely inactive. Recently Richmond and Sykes (1973) reported a classification of ß lactamases essentialy based on the profile of activity of these enzymes on various substrates and reaction with various inhibitors.

Keywords

Bacterial Strain Minimal Inhibitory Concentration Pseudomonas Aeruginosa Amide Bond Bacterial Resistance 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • Roger Labia
    • 1
  1. 1.Ecole Normale Superieure (ER 156 CNRS)Paris Cedex 05France

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