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Laboratory and Clinical Studies with Mecillinam

  • D. McGhie
  • M. J. Robertson
  • A. M. Geddes
  • K. C. L. Lim
Part of the Chemotherapy book series (CT, volume 5)

Abstract

Mecillinam (FL 1060) is a new antibiotic derived from a new class of Antibiotics, the 6β amidino penicillanic acids and despite a close structural similarity with other β lactam antibiotics, it has markedly different properties. II is much more active against gram negative organisms than gram positive organisms, and is more active than existing β lactam antibiotics in clinical use against Erlterobacteriae in general, and Escherichia coli and Salmonella species in particular.

Keywords

Urinary Tract Infection Enteric Fever Negative Organism Penicillanic Acid Regional Public Health 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Jonsson M. (1974) Is Chloramphenicol the Drug of Choice for the Treatment of Enteric Fever? Infection 2 1974 Nr. 3.Google Scholar
  2. Limson B.M. (1973) FL 1039, A new semisynthetic penicillin. Preliminary report on its use in Enteric Fever.Google Scholar
  3. Philippine Journal of Internal Medicine. Vol 11 No. 1Google Scholar
  4. Sales J.L. Wilson A. Rimmer D. 1975. 9th International Congress of Chemotherapy.Google Scholar
  5. Schiraldi.0.1974 Comments on a Clinical Trial with FL 1039, unpublished.Google Scholar

Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • D. McGhie
    • 1
  • M. J. Robertson
    • 1
  • A. M. Geddes
    • 1
  • K. C. L. Lim
    • 1
  1. 1.Regional Public Health Laboratory and Department of Communicable and Tropical DiseaseEast Birmingham HospitalEngland

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