Clinical Study of Bacampicillin in Urinary Tract Infections — A Comparison with Ampicillin
The purpose of the present study was to compare the clinical efficacy and tolerance of bacampicillin given in a twice daily dosage to ampicillin given in the normal three times daily dose to patients with urinary tract infection. Twenty three patients with an urinary tract infection were given either bacampicillin 400 mg. or 800 mg. x 2 or ampicillin 556 mg. x 3 in double blind technique for ten days. In this study bacampicillin given twice daily in equimolar or 1/2 equimolar doses to ampicillin gave as good clinical effect as ampicillin given three times daily. Many of our patients had predisposing factors like anatomical abnormalities, functional disturbancies and contributing diseases for urinary infections. No side effects were seen in the bacampicillin group but in one given ampicillin and iodine contrast an exanthema was seen.
KeywordsUrinary Tract Infection Urinary Infection Neurogenic Bladder Acute Pyelonephritis Prostatic Hypertrophy
Unable to display preview. Download preview PDF.