Meningococcal Prophylaxis: Problems with Minocycline

  • Dieter W. Gump
  • W. Lee Fanning
Part of the Chemotherapy book series (CT, volume 4)


Minocycline (7-dimethyl amino-6-demethyl tetracycline) is a tetracycline derivative that has been advocated as the drug of choice in the treatment of meningococcal carriers. The frequency and severity of side effects reported with minocycline in initial studies were infrequent and mild. We studied a group of thirty patients given minocycline as prophylaxis for a case of meningococcal meningitis who experienced a large number of side effects often limiting normal daily activity.


Respiratory Infection Meningococcal Disease Normal Daily Activity Meningococcal Meningitis Mild Side Effect 


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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • Dieter W. Gump
    • 1
  • W. Lee Fanning
    • 1
  1. 1.Department of Medicine, Infectious Disease UnitUniversity of Vermont College of MedicineBurlingtonUSA

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