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Neuromuscular Blocking Activity of Aminoglycoside Antibiotics

  • A. G. Paradelis
  • C. Triantaphyllidis
  • G. Logaras
Part of the Chemotherapy book series (CT, volume 4)

Abstract

Neuromuscular blockade is a recognized complication of anti -microbial therapy.There are now many experimental and clinical evidences to show that aminoglycoside antibiotics have an action at the neuromuscular junction.The aminoglycoside antibiotics are also potentially capable of interacting with curare or other muscle relaxants.The clinical significance of this interaction lies in the respiratory depression, prolonged apnoea or accidental death asso -ciated with the combination of muscle relaxants and aminoglycoside antibiotics.

Keywords

Calcium Chloride Neuromuscular Blockade Neuromuscular Blocking Aminoglycoside Antibiotic Methyl Sulfate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • A. G. Paradelis
    • 1
  • C. Triantaphyllidis
    • 1
  • G. Logaras
    • 1
  1. 1.Department of Experimental Pharmacology, Medical FacultyAristotelian University of ThessalonikiThessalonikiGreece

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