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Cholestyramine Induced Antibiotic Malabsorption

  • R. L. Parsons
  • Gillian M. Paddock
  • Gillian M. Hossack
Part of the Chemotherapy book series (CT, volume 4)

Abstract

Cholestyramine is a basic anion exchange resin which is increasingly being used in the treatment of hyperlipidaemia. Its main pharmacological action is to chelate with bile acids, preventing their normal enterohepatic recycling by the formation of an insoluble bile acid-resin complex. This bypasses the terminal ileum, the normal site for active reabsorption of bile acids back into the portal circulation, from which they re-enter the liver.

Keywords

Bile Acid Activate Charcoal Fusidic Acid Simultaneous Administration Pseudomembranous Colitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • R. L. Parsons
    • 1
  • Gillian M. Paddock
    • 1
  • Gillian M. Hossack
    • 1
  1. 1.Department of Clinical PharmacologyGuy’s Hospital Medical SchoolLondonUK

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