Cholestyramine Induced Antibiotic Malabsorption

  • R. L. Parsons
  • Gillian M. Paddock
  • Gillian M. Hossack
Part of the Chemotherapy book series (CT, volume 4)


Cholestyramine is a basic anion exchange resin which is increasingly being used in the treatment of hyperlipidaemia. Its main pharmacological action is to chelate with bile acids, preventing their normal enterohepatic recycling by the formation of an insoluble bile acid-resin complex. This bypasses the terminal ileum, the normal site for active reabsorption of bile acids back into the portal circulation, from which they re-enter the liver.


Bile Acid Activate Charcoal Fusidic Acid Simultaneous Administration Pseudomembranous Colitis 
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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • R. L. Parsons
    • 1
  • Gillian M. Paddock
    • 1
  • Gillian M. Hossack
    • 1
  1. 1.Department of Clinical PharmacologyGuy’s Hospital Medical SchoolLondonUK

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