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Sisomicin: Serum Half-Life and Distribution Space in Patients with Normal and Impaired Renal Function

  • S. Roth
  • K. G. Naber
  • M. Scheer
  • H. Lange
Part of the Chemotherapy book series (CT, volume 4)

Abstract

Sisomicin, a new aminoglykoside antibiotic, is now beeing introduced for clinical trials in the treatment of urinary tract infections. The purpose of this study was to determine some data of the pharmacokinetics in patients with normal and impaired renal function and to develop guidlines for appropriate dosage regimens for patients with renal insufficiency and in case of hemodialysis.

Keywords

Serum Creatinine Renal Insufficiency Normal Renal Function Impaired Renal Function Plasma Clearance 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • S. Roth
    • 1
    • 2
  • K. G. Naber
    • 1
    • 2
  • M. Scheer
    • 1
    • 2
  • H. Lange
    • 1
    • 2
  1. 1.Departments of Medicine and UrologyUniversity of Marburg.WuppertalGermany
  2. 2.Pharma ForschungszentrumBayer AGWuppertalGermany

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