Topical Chemotherapy and Prophylaxis in Thermal Injury
Definition of burn wound sepsis and development of animal models for reproducing lethal burn wound infection have made possible development of effective agents for control of wound infection and sepsis. Silver nitrate 0.5%, Sulfamylon and silver sulfadiazene are presently principal agents shown to be effective topical agents. Trade-off of level of effectiveness against side effects determines selection of agent. Monitoring criteria are essential if topical therapy is to be used safely.
KeywordsBacterial Count Silver Nitrate Thermal Injury Topical Therapy Cetyl Alcohol
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