Topical Chemotherapy and Prophylaxis in Thermal Injury

  • Robert B. Lindberg
  • B. A. PruittJr.
  • A. D. MasonJr.
Part of the Chemotherapy book series (CT, volume 3)


Definition of burn wound sepsis and development of animal models for reproducing lethal burn wound infection have made possible development of effective agents for control of wound infection and sepsis. Silver nitrate 0.5%, Sulfamylon and silver sulfadiazene are presently principal agents shown to be effective topical agents. Trade-off of level of effectiveness against side effects determines selection of agent. Monitoring criteria are essential if topical therapy is to be used safely.


Bacterial Count Silver Nitrate Thermal Injury Topical Therapy Cetyl Alcohol 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Asch, M.J., White, M.G. and Pruitt, B.A. Jr. (1970). Ann. Surg., 172, 946.PubMedCrossRefGoogle Scholar
  2. Bader, M.Z. and Bader, R.A. (1965). Am.J.Med., 38, 165.PubMedCrossRefGoogle Scholar
  3. Copeland, C.E. (1972). Therapeutic Adv. and New Clin. Implications, In: Symposium Univ. Miami School Med., Miami, Florida.Google Scholar
  4. Curreri, P.W., Shuck, J.M., Flemma, R.J., Lindberg, R.B. and Pruitt, B.A.Jr. (1969). Surg. Forum, 20, 506.PubMedGoogle Scholar
  5. Fox, C.L., Rappole, B.W. and Stanford, J.W. (1969). S.G. O., 128, 1021.Google Scholar
  6. Fox, C.L. (1968). Arch. Surg., 96, 184.PubMedCrossRefGoogle Scholar
  7. Georgiade, N.G. and Harris, W.A. (1972). Therapeutic Adv. and New Clin. Implications, In: Symposium Univ. Miami School of Med., Miami, Florida.Google Scholar
  8. Hartford, E.E. and Zefferin, S.E. (1972). J. Trauma, 9, 682.CrossRefGoogle Scholar
  9. Hummel, R.P., MacMillan, B.G. and Altemeier, W.A. (1970). Ann. Surg., 172, 370.PubMedCrossRefGoogle Scholar
  10. Lewis, S.R., Lynch, J.B., Blocker, T.G.Jr., Doyle, D.E. and Larson, D.L. (1970). Trans. 3rd Intl. Cong. Res. Burns, Prague, Hans Huber, Bern, p. 11.Google Scholar
  11. Lindberg, R.B., Moncrief, J.A., Switzer, W.E., Order, S.E. and Mills, W. (1965). J. Trauma, 5, 601.PubMedCrossRefGoogle Scholar
  12. Lowbury, E.J.L. (1970). Trans. 3rd Intl. Cong. Res. Burns, Prague,. Hans Huber, Bern., p. 138.Google Scholar
  13. Monafo, W.W. and Moyer, C.A. (1965). Arch. Surg. 91, 200.CrossRefGoogle Scholar
  14. Monafo, W.W., Brenton, L., Gravens, D. L., Kempson, R. and Moyer, C.A. (1966). Arch. Surg. 92, 212.PubMedCrossRefGoogle Scholar
  15. Moncrief, J.A., Lindberg, R.B., Switzer, W.E., Pruitt, B.A. Jr. (1966). J. Trauma, 6, 907.CrossRefGoogle Scholar
  16. Moncrief, J.A. (1968). Surgery, 63, 862.PubMedGoogle Scholar
  17. Moyer, C.A., Brentano, L., Gravens, D.L. and Morgraf, H.W. (1965). Arch. Surg., 90, 312.Google Scholar
  18. Polk, H.G. Jr. (1966). Ann. Surg., 164, 753.PubMedCrossRefGoogle Scholar
  19. Pruitt, B.A. Jr. (1970). Surgery, 68, 412.PubMedGoogle Scholar
  20. Pruitt, B.A. Jr. and Curreri, P.W. (1971). Arch. Surg., 103, 461.PubMedCrossRefGoogle Scholar
  21. Stone, H.H. (1971). J. Pediof. Surg., 3, 3.CrossRefGoogle Scholar
  22. Stone, H.H. and Kolb, L.D. (1971). J Trauma, 11, 386.CrossRefGoogle Scholar
  23. Teplitz, C., Davis, D. and Moncrief, J.A. (1964) J. Surg. Res., 4, 200.PubMedCrossRefGoogle Scholar
  24. Walker, H.L. and Mason, A.D. (1968). J. Trauma, 8, 1049.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • Robert B. Lindberg
    • 1
  • B. A. PruittJr.
    • 1
  • A. D. MasonJr.
    • 1
  1. 1.U.S. Army Institute of Surgical Research Fort SamHoustonUSA

Personalised recommendations