Topical Chemoprophylaxis in Surgery
Sepsis remains, in spite of 30 years of antibiotics, an important cause of illness and death. Figures are hard to come by, but the Report of the Public Health Laboratory Service (1960) on 2836 general surgical operations revealed clinical wound sepsis in 384 (13.5 per cent). In seven series reported from this hospital totalling 3761 operations, sepsis occurred in 513 (13.6 per cent). The incidence of infection in sutured surgical wounds is probably no less now than it was 40 years ago and it is only within the last few years that random controlled trials have yielded information of clinical value for its prevention.
KeywordsBrilliant Green Public Health Laboratory Surgical Wound Infection Postoperative Wound Infection Clean Operation
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