Cephalosporin-Tobramycin Activity Against Enterococci

  • F. R. Fekety
  • B. Bruce
  • D. Turrell
  • C. Work
  • J. Conway
Part of the Chemotherapy book series (CT, volume 3)

Summary

Anti-enterococcal synergism was readily demonstrable when cefazolin or cephalothin were combined with gentamicin or tobramycin, and Str. faecalis isolates were killed rapidly at attainable serum concentrations. The cephalosporins combined with amikacin were rarely synergistic, but ampicillin-amikacin was synergistic and bactericidal. Some of these newer combinations are worthy of further study in enterococcal infections.

Keywords

Penicillin Streptomycin Ampicillin Vancomycin Gentamicin 

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References

  1. Fekety, F.R. and Weiss, P. Antimicrob. Agents and Chemotherapy-1966, p. 156.Google Scholar
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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • F. R. Fekety
    • 1
  • B. Bruce
    • 1
  • D. Turrell
    • 1
  • C. Work
    • 1
  • J. Conway
    • 1
  1. 1.Department of Internal MedicineUniversity of Michigan Medical SchoolAnn ArborUSA

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