Cephalosporin-Tobramycin Activity Against Enterococci
Anti-enterococcal synergism was readily demonstrable when cefazolin or cephalothin were combined with gentamicin or tobramycin, and Str. faecalis isolates were killed rapidly at attainable serum concentrations. The cephalosporins combined with amikacin were rarely synergistic, but ampicillin-amikacin was synergistic and bactericidal. Some of these newer combinations are worthy of further study in enterococcal infections.
KeywordsMichigan Medical Enterococcal Infection Enterococcus Isolate Michigan Medical School Bactericidal Rate
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