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14C-Phenyl-Alanine Incorporation in the Presence of Veral Antibiotics on B. subtilis Transfection

  • A. Portoles
  • M. Espinosa
  • E. Garcia
  • M. T. Perez-Ureña
Part of the Chemotherapy book series (CT, volume 3)

Summary

Using a system for competence stimulation in B. subtilis six inhibitors of protein synthesis were tested through the 14C-phenyl-alanine incorporation, cell survival and competence. When a 20% mortality is produced, independently of the doses, gentamycin and lincomycin were the most active drugs. However, in absolute comparisons, tetracyclin molecules presented the maximal activity in such a sensitive biological system.

Keywords

Minimal Salt Medium Competence Development Transfection Procedure Serial Dilution Technique Absolute Comparison 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • A. Portoles
    • 1
  • M. Espinosa
    • 1
  • E. Garcia
    • 1
  • M. T. Perez-Ureña
    • 1
  1. 1.Inst. “Jaime Ferrán” of MicrobiologyC.S.I.C.MadridSpain

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