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Mode of Action of Chemotherapeutic Agents Against Bacteria Growing in a Continuous Flow Culture with Special Reference to the Antibacterial Effect of Cephalothin, Erythromycin and Kanamycin

  • Hirokazu Otaya
  • Atsushi Ozawa
  • Jinsaku Goto
Part of the Chemotherapy book series (CT, volume 3)

Summary

The present results show that the antibacterial mode of action of Cephalothin, Erythromycin and Kanamycin to bacteria growing in a continuous flow culture, a dynamic environment which the physiological state is assumed to be constract was significantly different from each other. The results obtained here would provide a useful information on proper dosage schedule of chemotherapeutic agent for in vivo study.

Keywords

Chemotherapeutic Agent Resistance Factor Culture Tube State Equi Initial Cell Count 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • Hirokazu Otaya
    • 1
    • 3
  • Atsushi Ozawa
    • 2
  • Jinsaku Goto
    • 2
  1. 1.Shionogi & Co., LtdJapan
  2. 2.Second National HospitalDoshomachi Higashi-ku, OsakaJapan
  3. 3.OsakaJapan

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