Abstract
Fifty-one patients with trichomonal vaginitis diagnosed by microscopicevaluation of the vaginal fluor were treated with Fasigyn (tinidazole)either in a cure of seven days 150mg. b.i.d., or in a single dose of2000mg. Both groups showed a cure-rate of 100% one week after initiation of the treatment. In the 7 day-group the cure-rate was still 100% 4 weeks after treatment as was the case in the single dose group on the 10th dayof the menstrual cycle following treatment. Eight weeks after treatment the cure-rates were 92% and 73%.
In the single dose group 3 patients showed nausea. As most patients from both groups had either recidivating or chronic vaginitis which had already been treated before these results are certainly warranting the use of Fasigyn as a first choice agent in the treatment of Trichomonas vaginalis infections.
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References
Trichomonas-Vaginitis. Nadere behandelingsmogelijkheden. J.Daels et al. Tijdschrift voor Geneeskunde 15–26e jaargang-1. 8. 70.
Trichomoniasis - Behandelung der Frau mit Tinidazole. J.Diwald. Wiener Medizinische Wochenschrift.121 (1971) no.24 (492)
History of the treatment of trichomoniasis. Robert Forgan. Brit.J.vener. Dis. (1972) 48, 522.
Zur Behandlung der Trichomoniasis beim Mann. J.Frick et al. Therapie Woche 21,6, 472 (1971).
Tinidazole, a New Antiprotozoal Agent: Effect on Trichomonas and other Protozoa. H.L.Howes, Jr.,et al. Antimicrobial Agents and Chemotherapy- 1969,p. 261.
Perorale Behanlung der Trichomonadenkolpitis mit Fasigyn. R.Liechti. Schweiz.Z.Gynäk.Geburtsh. 2, 229–235 (1971).
Tinidazole, a Potent New Antiprozoal Agent. M.W.Miller et al. Antimicrobial Agents and Chemotherapy - 1969, 257.
Tinidazole and Metronidazole Pharmacokinetics in Man and Mouse. J.A.Taylor et al. Anticrobial Agents and Chemotherapy - 1969, 267.
The Pharmacokinetics of Metronidazole and Tinidazole in Man. P.G.Welling et al. Arzneimittel–Forschung (Drug research) 22, 2128–2132 (1972).
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© 1976 Plenum Press, New York
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Rhemrev, P.E.R., Kosasih, F. (1976). Trichomonas Vaginitis, and its Treatment with Tinidazole. In: Williams, J.D., Geddes, A.M. (eds) Special Problems in Chemotherapy. Chemotherapy, vol 3. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3120-9_26
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DOI: https://doi.org/10.1007/978-1-4684-3120-9_26
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