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Incidence of Drug Resistance on the Mycobacterial Strains Isolated from Treated and Untreated Patients

  • J. A. Garcia
  • M. C. Saenz
  • J. Prieto
  • F. Martin
Part of the Chemotherapy book series (CT, volume 3)

Summary

The resistances of 308 strains of mycobacteria were studied by means of the technique of Canetti, Rist and Grosset, against seven antituberculosis drugs. Two hundred and ninety-four of the strains were identified as M. tuberculosis, and fourteen as atypical mycobacteria. All strains were of human origin.

The strains of M. tuberculosis isolated from untreated patients (110 strains) were sensitive to Rifampicin and Ethambutol, while those isolated from treated patients showed variable resistance to the drugs used. The highest percentages of resistances were those of Isoniazid (42.3%), Streptomycin (29.8%) and p-Aminosalicylic acid (22%).

The atypical mycobacteria strains showed a higher resistance disregarding their origin from treated or untreated patients.

Keywords

Salicylic Acid Untreated Patient Sodium Lauryl Sulfate Lauryl Sulfate Antituberculosis Drug 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. CANETTI, G.; RIST, N., and GROSSET, J, (1963). - “Mesure de la sensibilité du bacille tuberculeux aux drogues antibacillaires par la méthode des proportions. Méthodologie, cri-téres de résistance, résultats interprétation”. - Rev. Tub, Pneu-mol. 27. 217Google Scholar
  2. TACQUET, A., and TISON, F. (1961). “Nouvelle téchnique dtisolement des mycobactéries par le lauryl-sulfate de sodium”. Ann. Inst. Pasteur 100, 676.Google Scholar

Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • J. A. Garcia
    • 1
  • M. C. Saenz
    • 1
  • J. Prieto
    • 1
  • F. Martin
    • 1
  1. 1.Microbiology Department, Faculty of MedicineUniversity of SalamancaFonseca, 2Spain

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