Are There Two Forms of Nicotinic Acetylcholine Receptor?

  • T. Mittag
  • T. Massa
  • S. Gross
Part of the Advances in Behavioral Biology book series (ABBI, volume 24)


The purified nicotinic acetylcholine receptor (AChR) is currently being intensively studied to elucidate the molecular events involved in transduction and amplification of ACh binding into a rise in ion permeability. For these purposes AChR from the richest source, the electric organs from Torpedo or Electrophorus, have been used. Progress in this area has been described in several recent reviews. Although mammalian muscle is quantitatively a much less suitable source for AChR, it has provided important information on the dynamics of the receptor molecule (localization, synthesis and degradation) and information on the autoimmune aspects of Myasthenia Gravis (V. Lennon, this volume).


Nicotinic Acetylcholine Receptor Toxin Binding Myasthenic Patient Thymus Extract Label Receptor 
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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • T. Mittag
    • 1
  • T. Massa
    • 1
  • S. Gross
    • 1
  1. 1.Department of Pharmacology, Mt. Sinai School of MedicineCity University of New YorkNew YorkUSA

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