Effect of Atropine on Acetylcholine Metabolism in the Mouse Brain
Studies on different ways of killing animals have demonstrated that their brain concentrations of ACh and choline (Ch) are very sensitive to postmortem changes (9). When spinal dislocation is employed for this purpose we have found concentrations of ACh and Ch in whole brain of mice of about 16 and 60 nmol/g, respectively (5). When focussed microwave irradiation is used to kill the animals, levels of about 25 and 35 nmol/g are found instead.
KeywordsMicrowave Irradiation Turnover Rate Pulse Injection Atropine Sulfate Labile Pool
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