Abstract
Discussion on the mode of action of psychoactive drugs are often based on the changes in brain monoamine content, although any change in content induced by a drug is not necessarily the best indicator of its mechanism of action. Electrophysiological methods, by which the receptors of central neuron for biogenic amines may be characterized as to location and function, still fail to provide convincing evidence of the mode of action of biogenic amines. With these techniques the most commonly observed action of norepinephrine (NE) in most parts of the central nervous system is depression of firing (7, 27–29). Although the typical actions of neurotransmitters on cell excitability in most regions of the neural axis have been described, relatively less information is available on the underlying mechanisms. In the last few years, however, neurochemical evidence has also been obtained concerning the pre- and post-synaptic action of different neurotransmitters in the CNS.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Andersen, P. and Curtis, D.R. (1964): Acta Physiol. Scand. 61: 100–120.
Barbeau, A. (1975): Canad. J. Neurol. Sci. 2:81–85.
Beani, L., Bianchi, B., Clementina, C. and Crema, A. (1969): Brit. J. Pharmacol. 36:1–17.
Birkmayer, W. and Hornykiewicz, O. (1961): Wien. Klin. Wsch. 73:787–788.
Biscoe, T.J. and Straughan, D.W. (1966): J. Physiol. (Lond.) 183: 341–359.
Bloom, F. E., Oliver, A. P. and Salmoiraghi, G. C. (1973): Int. J. Neuropharmacol. 2:181–193.
Bloom, F.E. (1975): In: Handbook of Psychopharmacology, Vol.6, Biogenic Amine Receptors, (Eds.) L.L. Iversen, S.D. Iversen and S. H. Snyder, Plenum Press, New York, pp. 1–61.
Christ, D.D. and Nishi, S. (1971): J. Physiol. (Lond.) 213:107–117.
Costall, B., Naylor, R.J. and Pycock, C. (1976): Eur. J. Pharmacol. 35:275–283.
Dawes, P.M. and Vizi, E.S. (1973): Brit. J. Pharmacol. 48:225–232.
Fibiger, H. C. and Grewaal, D.S. (1974): Life Sci. 15:57–63.
Furness, J.B. and Costa, M. (1974): Physiol. Rev. 69:1–51.
Fuxe, K., Hokfelt, T. and Nilsson, O. (1964): Z. Zellforsch. Histochem. 63:701.
Fuxe, K., Hamberger, B. and Hokfelt, T. (1964): Brain Res. 8: 125–131.
Greengard, P. and McAffee, D.A. (1972): Biochem. Soc. Symp. 36:87–102.
Guyenet, P. G., Agid, Y., Javoy, F., Beaujouan, J. C., Rossier, J. and Glowinski, J. (1975): Brain Res. 84:227–244.
Jones, B.E., Guyenet, P., Cheramy, A., Gauchy, C. and Glowinski, J. (1973): Brain Res. 64:355–369.
Klawans, H. L. Jr. (1970): Eur. Neurol. 4:148–163.
Knoll, J. and Vizi, E.S. (1970): Brit. J. Pharmacol. 40:554–555.
Knoll, J. and Vizi, E.S. (1971): Brit. J. Pharmacol. 42:263–272.
Kosterlitz, H.W., Lyden, R.J. and Watt, A.J. (1970): Brit. J. Pharmacol. 39:398–413.
McKenzie, G.M. and Viik, K. (1975): Exp. Neurol. 46:229–243.
McLennan, H. and York, D.H. (1966): J. Physiol. (Lond.) 187:163–175.
Paton, W.D. and Vizi, E.S. (1969): Brit. J. Pharmacol. 35:10–28.
Perry, T.L., Hansen, S. and Kloster, M. (1973): New Eng. J.Med. 288:337–342.
Petri, G., Szenohradszky, J. and Porszasz-Gibiszer, K. (1971): Surgery 70:359–367.
Phillis, J.W. and Kostopoulus, G.K. (1976): Life Sci. 17:1085–1094.
Phillis, J.W. (1976): In: Taurine, (Eds.) R. Huxtable and A. Barbeau, Raven Press, New York, pp. 209–223.
Phillis, J.W., Tebecis, A.K. and York, D.H. (1968): Eur. J. Pharmacol. 1:471–475.
Stadler, H., Lloyd, K., Gadea-Ciria, K.G. and Bartholini, G. (1973): Brain Res. 55:476–480.
Trabucchi, M., Cheney, D., Racagni, G. and Costa, E. (1974): Nature 249:664–666.
Vizi, E.S. (1968): Arch. Pharmacol. 259:199–200.
Vizi, E.S. and Knoll, J. (1971): J. Pharm. Pharmacol. 23:918–925.
Vizi, E.S. (1972): J. Physiol. (Lond.) 226:95–117.
Vizi, E.S. (1973): Brit. J. Pharmacol. 47:765–777.
Vizi, E.S., Ronai, A. and Knoll, J. (1974): N.-S. Arch. Pharmacol. Suppl. 285:R89.
Vizi, E.S. (1974): J. Neural Trans. Suppl. 11:61–78.
Vizi, E.S. (1975): In: Subcortical Mechanisms and Sensorimotor Activities (Ed.) T.L. Friggesi, Hans Huber, Bern, pp.63–87.
Vizi, E.S. (1976): In: Physiology of Smooth Muscle, (Eds.) E. Bulbring and M. F. Shuba, Raven Press, New York, pp. 357–367.
Vizi, E.S., Ronai, A., Harsing, L.G. Jr. and Knoll, J. (1977): Polish J. Pharmacol. (in press).
Westfall, T. C., Besson, M.J., Giorguieff, M.F. and Glowinski, J. (1976): N.-S. Arch. Pharmacol. 292:279–287.
Wikberg, J. (1977): Acta Physiol. Scand. 99:190–207.
York, D.H. (1970): Brain Res. 20:223–249.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1978 Plenum Press, New York
About this chapter
Cite this chapter
Vizi, E.S., Ronai, A., Harsing, L.G., Knoll, J. (1978). Presynaptic Modulation by Norepinephrine and Dopamine of Acetylcholine Release in the Peripheral and Central Nervous System. In: Jenden, D.J. (eds) Cholinergic Mechanisms and Psychopharmacology. Advances in Behavioral Biology, vol 24. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3096-7_41
Download citation
DOI: https://doi.org/10.1007/978-1-4684-3096-7_41
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-3098-1
Online ISBN: 978-1-4684-3096-7
eBook Packages: Springer Book Archive