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Radioimmunoassay for Acetylcholine

  • S. Spector
  • A. M. Felix
  • J. P. M. Finberg
Part of the Advances in Behavioral Biology book series (ABBI, volume 24)

Abstract

There are a number of analytical methods for the determination of tissue concentrations of ACh (4), and each of these various methods offers particular advantages. We would like to present a procedure for the development of a radioimmunoassay (RIA) for the neurotransmitter substance of the cholinergic nervous system, and preliminary data on the use of RIA to quantitate levels of ACh in guinea pig brain.

Keywords

Myenteric Plexus Unlabelled Ligand Bovine Gamma Globulin Zealand Albino Rabbit Neurotransmitter Substance 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Berson, S.A. and Yalow, R.S. (1959): J. Clin. Invest. 38:1976.Google Scholar
  2. 2.
    Berson, S.A. and Yalow, R.S. (1966): The Harvey Lectures, The Harvey Soc., N. Y. Acad. Med., The Maple Press, Inc.Google Scholar
  3. 3.
    Butler, V.P. Jr. (1975): J. Immun. Meth. 7:1.CrossRefGoogle Scholar
  4. 4.
    Hanin, I. (1974): Choline and Acetylcholine: Handbook of Chemical Assay Methods, Raven Press, New York.Google Scholar
  5. 5.
    Landsteiner, K. (1946): Specificity of Serological Reactions, Harvard University Press, Cambridge.Google Scholar
  6. 6.
    Spector, S., Berkowitz, B., Flynn, E.J. and Peskar, B. (1973): Pharmacol. Rev. 25:281.PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • S. Spector
    • 1
  • A. M. Felix
    • 1
  • J. P. M. Finberg
    • 1
  1. 1.Roche Institute of Molecular Biology and Hoffman-LaRoche, Inc.NutleyUSA

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