Cocaine: 1884–1974

  • Craig Van Dyke
  • Robert Byck
Part of the Advances in Behavioral Biology book series (ABBI, volume 21)


Cocaine, because of its unique properties as a local anesthetic, is still widely used in medicine some one hundred years after its introduction to Europe as a panacea. Karl Koller’s discovery of the local anesthetic action of cocaine defined its legitimate medical usage. Today, cocaine is a drug of abuse that has dramatically increased in popularity. It is reported to produce an intense euphoria 3–5 minutes after intranasal application and thereby has gained the reputation of being the “champagne of drugs.”


Local Anesthetic Nictitate Membrane Morphine Sulfate Sympathomimetic Amine Sympathetic Nerve Terminal 
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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • Craig Van Dyke
    • 1
  • Robert Byck
    • 1
  1. 1.Yale University School of MedicineNew HavenUSA

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