The contributions of the septum to physiological and behavioral responses have been frequently linked with those of the hypothalamus. The early observations of changes in blood pressure, heart rate and respiration from stimulation of the septum (19,20,41) were considered in terms of effects on the hypothalamus and lower brain stem. In the classical study of Kaada (18) the autonomic and somatomotor responses elicited by stimulation of the septum and other limbic forebrain structures were attributed to effects on the hypothalamus. The demonstrations of the rage syndrome (6) and of polydipsia (17) following lesions of the septum were considered to be the result of removing inhibitory effects on neural systems represented in the hypothalamus for emotional expression (3) and drinking (43), respectively. It is not surprising, therefore, that a presentation on septal-hypothalamic relationships has been included in this symposium devoted to the septum.
KeywordsLateral Hypothalamus Septal Lesion Medial Septum Hypothalamic Neuron Lateral Septum
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