Hormone-Behavior Analysis

  • Richard E. Whalen
Part of the Advances in Behavioral Biology book series (ABBI, volume 12)


Current research on hormones and behavior deals with two distinct, but related aspects of hormone action, the effects of hormones on behavior controlled by a fixed substrate and the effects of hormones on the development and differentiation of the substrate for behavior. These have often been called the “activating” and “organizing” actions of hormones, respectively. Within the context of both of these modes of action of hormones, I would like to discuss certain methodological considerations and contemporary approaches to the endocrinological analysis of behavior.


Sexual Behavior Mating Behavior Hormone Action Testosterone Propionate Estradiol Benzoate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. Anderson, K.M. and Liao, S. Selective retention of dihydro-testosterone by prostatic nuclei. Nature, 1968, 219, 277–279.PubMedCrossRefGoogle Scholar
  2. Baum, M.J. and Vreeburg, J.T.M. Copulation in castrated male rats following combined treatment with estradiol and dihydrotestosterone. Science, 1973, 182, 283–285.PubMedCrossRefGoogle Scholar
  3. Beach, F.A. Hormonal factors controlling the differentiation development and display of copulatory behavior in the ramstergig and related species. In The Biopsychology of Development (E. Tobach, L.R. Aronson and E. Shaw, Eds.) Academic Press, New York, 1971, 249–296.Google Scholar
  4. Beach, F.A. and Fowler, H. Individual differences in the response of male rats to androgen, J. comp, physiol. Psychol., 1959, 52, 50–52.CrossRefGoogle Scholar
  5. Beyer, C., Larsson, K., Perez-Palacios, G. and Morali, G. Androgen structure and male sexual behavior in the castrated rat. Horm. Behav., 1973,4, 99–107.CrossRefGoogle Scholar
  6. Beyer, C. and Rivaud, N. Differential effect of testosterone and dihydrotestosterone on the sexual behavior of prepuberally castrated male rabbits. Horm. Behav., 1973, 4, 175–180.CrossRefGoogle Scholar
  7. Bruchovsky, N. and Wilson, J.D. The conversion of testosterone to 5 a -androstan-17 B-ol-3-one by rat prostate. J. Biol., Chem., 1968, 243, 5953–5960.Google Scholar
  8. Clemens, L.G., Wallen, K. and Gorski, R.A. Mating behavior: Facilitation in the female rat after cortical application of potassium chloride. Science, 1967, 157, 1208–1209.PubMedCrossRefGoogle Scholar
  9. Davidson, J.M. Characteristics of sex behaviour in male rats following castration. Anim. Behav., 1966, 79, 266–272.CrossRefGoogle Scholar
  10. Davidson, J.M. Activation of the male rats sexual behavior by intracerebral implantation of androgen. Endocrinology, 1966, 79, 783–794.PubMedCrossRefGoogle Scholar
  11. Edwards, D.A., Early androgen stimulation and aggressive behavior in male and female mice. Physiol. Behav., 1969, 4, 333–338.CrossRefGoogle Scholar
  12. Edwards, D.A. Neonatal administration of androstenedione, testosterone or testosterone propionate: Effects on ovulation, sexual receptivity and aggressive behavior in female mice. Physiol. Behav., 1971, 6, 223–228.PubMedCrossRefGoogle Scholar
  13. Feder, H.H. The comparative actions of testosterone propionate and 5 a -androstan-17 ß -ol-3-one propionate on tile reproductive physiology and morphology of male rats. J. Endocr., 1971, 51, 241–252.PubMedCrossRefGoogle Scholar
  14. Gorzalka, B.B. and Whalen, R.E. Genetic regulation of hormone action: Selective effects of progesterone and dihydro-progesterone C5 a -pregnane-3,20-dione) on sexual receptivity in mice. Steroids, 1974, in press.Google Scholar
  15. Goy, R.W. and Goldfoot, D.A. Hormonal influence on sexually dimorphic behavior. In Handbook of Physiology: Endocrinology II. (R.O. Greep and E.B. Astwood, Eds,). Am. Physiol. Soc., Washington, D.C., in press.Google Scholar
  16. Grunt, J.A. and Young, W.C. Differential reactivity of individuals and the response of the male guinea pig to testosterone propionate. Endocrinology, 1952, 51, 237–248,PubMedCrossRefGoogle Scholar
  17. Grunt, J.A, and Young, W.C. Consistency of sexual behavior patterns in individual male guinea pigs following castration and androgen therapy. J. comp, physiol. Psychol., 1953, 46, 138–144.CrossRefGoogle Scholar
  18. Guhl, A.M. Gonadal hormones and social behavior in infrahuman vertebrates. In Sex and Internal Secretions, (W.C. Young, Ed.) Williams and Wilkins Co., Baltimore, 1961, vol. 2 Pp 1240–1267.Google Scholar
  19. Harris, G.W., Michael, R.P, and Scott, P.O. Neurological site of action of stilboestrol in eliciting sexual behaviour. In Neurological Basis of Behavior. (G.E.W. Wolstenholme and CM. O’Connor, Eds.) Little, Brown and Co., Boston, 1958, Pp. 236–251.Google Scholar
  20. Johnston, P. and Davidson, J.M. Intracerebral androgens and sexual behavior in the male rat. Horm. Behav., 1972, 3, 345–357.CrossRefGoogle Scholar
  21. Karli, P. Hormones Steroides et comportement d’agression interspécifique Rat-Souris. J. de Physiol., (Paris), 1958, 50, 346–347.Google Scholar
  22. Kierniesky, N.C. and Gerall, A.A. Effects of testosterone propionate implants in the brain on the sexual behavior and peripheral tissues of the male rat. Physiol. Behav., 1973, 11, 633–640.PubMedCrossRefGoogle Scholar
  23. Luttge, W.G. Activation and inhibition of isolation induced inter-male fighting behavior in castrate male CD-I mice treated with steroidal hormones. Horm. Behav., 1972, 3, 71–81,PubMedCrossRefGoogle Scholar
  24. Luttge, W.G. and Hall, N.R. Androgen-induced agonistic behavior in castrate male Swiss-Webster mice: Comparison of four naturally occurring androgens. Behav. Biol., 1973, 8, 725–732.PubMedCrossRefGoogle Scholar
  25. Naftolin, F., Ryan, K.J. and Petro, Z. Aromatization of androstenedione by the anterior hypothalamus of adult male and female rats. Endocrinology, 1972, 90, 295–298.PubMedCrossRefGoogle Scholar
  26. Owen, K., Peters, P.J. and Bronson, F.H. Effects of intracerebral implants of testosterone propionate in internale aggression in the castrated male mouse. Horm. Behav., 1974, 5, 83–92.PubMedCrossRefGoogle Scholar
  27. Payne, A.P. The effect of androgens on isolâtion-induced aggression in the male golden hamster. J. Endocr., 1973, 57, xxxvi.Google Scholar
  28. Phoenix, C.H., Goy, R.W., Gerall, A.A. and Young, W.C. Organizing action of prenatally administered testosterone propionate on the tissues mediating mating behavior in the female guinea pig. Endocrinology, 1959, 65, 369–382.PubMedCrossRefGoogle Scholar
  29. Quadagno, D.M., Shryne, J. and Gorski, R.A. The inhibition of steroid-induced sexual behavior by intrahypothalamic Actinomycin-D. Horm. Behav., 1971, 2, 1–10.CrossRefGoogle Scholar
  30. Reddy, V.V.R., Naftolin, F. and Ryan, K.J. Aromatization in the central nervous system of rabbits: Effects of castration and hormone treatment. Endocrinology, 1973, 92, 589–594.PubMedCrossRefGoogle Scholar
  31. Resko, J.A. Endocrine control of adrenal progesterone secretion in the ovariectomized rat. Science, 1969, 164,Google Scholar
  32. Sodersten, P. Estrogen-activated sexual behavior in male rats. Horm. Behav., 1973, 4, 247–256,CrossRefGoogle Scholar
  33. Whalen, R.E. Estrogenprogesterone induction of mating in female rats. Horm. Behav., 1974, in press.Google Scholar
  34. Whalen, R.E. and Luttge, W.G. Testosterone, androstenedione and dihydrotestosterone: Effects on mating behavior of male rats. Horm. Behav.» 1971, 2, 117–125.CrossRefGoogle Scholar
  35. Whalen, R.E. and Rezek, D.L. Localization of androgenic metabolites in the brain of rats administered testosterone or dihydrotestosterone, Steroids1912, 20, 717–725.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • Richard E. Whalen
    • 1
  1. 1.University of CaliforniaIrvineUSA

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