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The Chemical Coding Via the Cholinergic System: Its Organization and Behavioral Implications

  • A. G. Karczmar
Part of the Advances in Behavioral Biology book series (ABBI, volume 10)

Abstract

The central cholinergic synapses which constitute the subject of this paper are those at which the transmission between the presynaptic and the postsynaptic neuron — or, more precisely, between the presynaptic nerve terminal and the postsynaptic membrane — is mediated by acetylcholine (ACh); a complication may arise from the fact that at certain, non-cholinergic synapses ACh may play a modulatory, facilitatory rather than transmissive role. In view of the wide occurrence (cf. below) of the cholinergic synapses or modulations, the cholinergic system must participate significantly in brain functions and behavioral processes* In fact, several participants of this Symposium discussed the cholinergic participation in the appetitive and thermal control (R.D. Myers), in conditioning and learning (H. Brust-Carmona), in aggression (D.J. Reis), and in certain phases of sleep (P. Morgane); related aspects of the cholinergic system were described by others (Domino, 1968; Domino et al., 1968; Bovet-Nitti, 1965; Aprison, 1965; Stein, 1968; Karczmar et al., 1972; Karczmar, 1971).

Keywords

Cholinergic System Paradoxical Sleep Cholinergic Synapse Chemical Code Central Cholinergic System 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • A. G. Karczmar
    • 1
    • 2
  1. 1.Department of PharmacologyLoyola University Medical CenterMaywoodUSA
  2. 2.Institute for Mind, Drugs and BehaviorLoyola University Medical CenterMaywoodUSA

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