The Possible Nature of Sleep Inducing Brain Perfusates: Their Relationship to Seizure Inhibition

  • R. R. Drucker-Colin
Part of the Advances in Behavioral Biology book series (ABBI, volume 10)


The search for a relationship between a particular neurotransmitter and a certain type of behavior has become somewhat of a scientific vogue. Yet, despite the vast literature on the subject and despite some direct demonstrations that neurohumors are released as a result of synaptic activity or nerve function (McLennan, 1964; Baldessarini and Kopin, 1966; Szerb, 1967; Yaksh and Myers, 1972), there is little evidence showing that a particular behavior or behavioral component is induced as a result of a neurohumor acting locally at a brain site. As Kety (1967) has suggested)when we come to behavioral-neurohumoral relationships, we find that most of the evidence depends on indirect pharmacological studies, whose drawbacks are many, with perhaps the most important one being related to the multiplicity of effects induced by any one drug.


Slow Wave Sleep Brain Perfusate Focal Epilepsy Electroconvulsive Shock Epileptic Discharge 
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Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • R. R. Drucker-Colin
    • 1
  1. 1.Instituto Miles de Terapéutica ExperimentalMéxico 22, D.F.Mexico

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