Regulation of Catecholamine Biosynthesis: Tyrosine Hydroxylase and Dihydropteridine Reductase

  • José M. Musacchio
Part of the Advances in Behavioral Biology book series (ABBI, volume 1)


It is generally accepted that catecholamines have an important role in the regulation of several brain functions, and there is increasing evidence that they may be involved in the development of certain affective disorders. Most of the agents used in the treatment for depression and mania are known to affect either the synthesis, storage, and release of catecholamines or the central adrenergic receptors. These brief considerations are sufficient to justify an examination of the enzymes that are considered important for the regulation of catecholamine biosynthesis.


Tyrosine Hydroxylase Adrenal Medulla Tritiated Water Chromaffin Granule Catecholamine Synthesis 
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Copyright information

© Plenum Press, New York 1971

Authors and Affiliations

  • José M. Musacchio
    • 1
  1. 1.New York University School of MedicineNew YorkUSA

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