Clinical Implications of Immunity to Oncogenic Viruses

  • Paul H. Levine
Part of the Contemporary Topics in Immunobiology book series (CTI, volume 6)


The evidence pointing to a viral etiology for at least some forms of human cancer, a possibility that has long been considered on the basis of animal studies, has continued to accumulate to such an extent that viral oncologists must now reevaluate their clinical and experimental data in order to consider which specific approaches are now ready for clinical trials. Although ethical restrictions continue to inhibit attempts to prove that specific viruses cause certain human tumors, as outlined by Bryan et al. (1967; Bryan, 1962), epidemiological studies have been able to suggest not only which human tumors are most likely to be caused by infectious agents (Burkitt, 1962; Cole et al., 1968; Correa and O’Conor, 1971; Heath and Hasterlik, 1963; Kessler, 1974; Levine, 1974; Levine and Gravell, 1975; Morrow et al., 1971) but some have even suggested the pattern of the agents’ transmission (Kessler, 1976; Vianna et al., 1971).


Cervical Cancer Oncogenic Virus Familial Medullary Thyroid Carcinoma Herpesvirus Saimiri West Nile Region 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • Paul H. Levine
    • 1
  1. 1.Laboratory of Viral Carcinogenesis National Cancer InstituteNational Institutes of HealthBethesdaUSA

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