Characteristics of the Agglutinin in the Scorpion, Androctonus australis

  • Zacharie Brahmi
  • Edwin L. Cooper


The hemolymph of most invertebrates contains naturally occurring hemagglutinins with specificities comparable to the isohemagglutinins present in vertebrate sera (Tyler, 1946; Cushing et al., 1963; Tripp, 1966; Marchalonis and Edelman, 1968; McKay et al., 1969). Similarly, the hemolymph of some invertebrates, such as the oyster (Tripp, 1966), the horseshoe crab (Marchalonis and Edelman, 1968), and the crayfish (McKay and Jenkin, 1969) contains elements analogous to vertebrate antibodies, for both increase the rate of phagocytosis of erythrocytes. Several investigators have tried to characterize the factors involved in invertebrate phagocytosis. Acton et al. (1969), for example, observed that an oyster agglutinin has a sedimentation coefficient of 33 S and that it can be dissociated into polypeptide chains having a molecular weight of 20,000.


Horseshoe Crab Normal Human Serum Sedimentation Coefficient Agglutinate Titer Cellulose Acetate Electrophoresis 
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Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • Zacharie Brahmi
    • 1
  • Edwin L. Cooper
    • 2
  1. 1.Institut Pasteur d’AlgerieAlgiersAlgeria
  2. 2.Department of Anatomy, School of MedicineUniversity of CaliforniaLos AngelesUSA

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