Graft Rejection and the Regulation of Length in Hydra viridis
At a recent meeting of comparative immunologists an argument took place about how to conduct research on evolutionary questions. The speaker had said that to trace the origins of the immune system the essential question was, “What characteristics of the primitive organism could give rise to the immune system?” not, “What characteristics of the immune system are found in primitive organisms?” The former question acknowledges the ambiguous antecedents of immunity while the latter question predetermines the answer and limits the potential for research. The moderator reproachfully argued that proceeding without the classical definitions of immunity justifies any sort of research as immunology. He was urged to work on primitive organisms to break down his vertebrate- bound immunologic chauvinism.
KeywordsGraft Rejection Positional Information Diffusion Gradient Neutral Zone Donor Animal
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