Septohippocampal Interface

  • Ervin William Powell
  • Garth Hines


The hippocampal formation is usually understood to include the hippocampal gyrus (or at least the parahippocampal portion of that gyrus), the hippocampus proper (cornu ammonis), and the fascia dentata (Fig. 1). The hippocampal rudiment, located in the rostral septal area and ventral to the genu of the corpus callosum, was suggested by Hines (1922) as the anlage of the fascia dentata. Furthermore, its cells are cytoarchitectonically similar to the granular cells of the fascia dentata. However, an adequate comparative cell study of the various dense granule cell areas of the brain (e.g., the fascia dentata, olfactory tubercle, hippocampal rudiment, and pyriform cortex) has not been performed, so whether these areas are rudimentary portions of the hippocampus or relatively undifferentiated cell clusters is not known. In primitive animals (Hoffman, 1967), the hippocampus forms a medial archicortex along the major length of the brain, forming a pre- and postcommissural hippocampus. In higher animals, the hippocampus gradually comes to lie entirely in the temporal lobe, as it does in the squirrel monkey. The dorsal hippocampus is prominent in the rat, with very little ventral hippocampus, while the cat and dog have a nearly equal representation of both the dorsal and ventral portions.


Dorsal Hippocampus Medial Forebrain Bundle Ventral Hippocampus Mammillary Body Septal Area 


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Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  • Ervin William Powell
    • 1
  • Garth Hines
    • 2
  1. 1.Department of AnatomyUniversity of Arkansas School of MedicineLittle RockUSA
  2. 2.Department of PsychologyUniversity of Arkansas at Little RockLittle RockUSA

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