Putative Glucocorticoid Receptors in Hippocampus and Other Regions of the Rat Brain

  • Bruce S. McEwen
  • John L. Gerlach
  • David J. Micco


It has been known for some time from neuroendocrine and behavioral studies that the brain is both a master controller of endocrine function and a target for these endocrine secretions. There exist complex feedback interactions between endocrine secretions and the brain which not only control the secretion of hypothalamic and pituitary hormones but also influence neural activity underlying behavior. It is only quite recently that we have come to appreciate the role of the entire limbic brain, and not just the hypothalamus, in these endocrine-brain interactions.


Paradoxical Sleep ACTH Secretion Adrenal Steroid Plasma Corticosterone Level Bilateral Adrenalectomy 
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Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  • Bruce S. McEwen
    • 1
  • John L. Gerlach
    • 1
  • David J. Micco
    • 1
  1. 1.The Rockerfeller UniversityNew YorkUSA

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