Carcinogenicity and Teratogenicity
Tumors are abnormal masses of tissue that grow and persist independently of surrounding structures. They have no physiologic function. Tumors that spread to other tissues (metastasize), or are transplantable to other tissues, are called malignant tumors, or cancers. Tumors that are usually encapsulated and do not metastasize are benign. Since benign tumors may develop into malignant tumors, the U.S. Environmental Protection Agency (Gibney, 1975) classified as oncogenic those substances capable of inducing either type of tumor. The relationships of tumors that are involved with mineral toxicities are presented in Table 5–1.
KeywordsArsenic Trioxide Nickel Sulfide Cobalt Sulfide Placental Membrane Essential Trace Metal
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