Biochemical Characterization of a Clonal Line of Neuroblastoma
Study of the molecular mechanism of differentiation has been hampered by, among other difficulties, the complexity of the systems investigated, where several changes occur at the same time and overlap each other. The possibility of selecting a homogeneous cellular population in which only a limited step of cellular maturation occurs may provide a useful system for studying cell differentiation.
KeywordsSuspension Culture Monolayer Cell Neuroblastoma Cell Neurite Outgrowth Sucrose Gradient
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- Augusti-Tocco, G. 1971. In F. A. Morris, P. G. Nelson, and F. H. Ruddle (eds.). Contributions of clonal systems to neurobiology; Neurosci. Res. Bull., Vol. 11.Google Scholar
- Augusti-Tocco, G., Sato, G. H., Claude, P., and Potter, D. D. 1970. Clonal cell lines of neurons, pp. 109–120. In H. A. Padykula (ed.) Control Mechanisms in the Expression of Cellular Phenotypes. Academic Press, New York.Google Scholar
- Augusti-Tocco, G., Casola, L., and Grasso, A. 1973. Neuroblastoma cells and 14-3-2, a brain specific protein. Submitted for publication.Google Scholar
- Furshpan, E. J., and Potter, D. D. 1968. Low-resistance junctions between cells in embryos and tissue culture, pp. 95–127. In A. A. Moscona, and A. Monroy, (eds.). Current Topics of Developmental Biology, Vol. 3. Academic Press, New York.Google Scholar
- Jacob, M. 1971. RNA metabolism and differentiation of the central nervous system. In Abstracts 7th FEBS Meeting, Varna, p. 70.Google Scholar
- Lumsden, C. E. 1968. Nervous tissue in culture, pp. 67–140. In G. H. Bourne (ed.) The Structure and Function of Nervous Tissue. Academic Press, New York.Google Scholar
- Sidman, R. L. 1972. Cell interactions in developing mammalian central nervous system, pp. 1–13. In L. G. Silvestri (ed.). Cell Interactions. North-Holland, Amsterdam and London.Google Scholar