Recombination and Postreplication Repair
The available data concerning postreplication repair are summarized. In Escherichia coli, recombination is implicated in this repair because the recA + gene is necessary and because strand exchanges occur that extend over long regions. Other experiments involving phage-induced resistance also point to an interrelation between recombination and repair. In this phenomenon, gene products of λ bacteriophage are introduced into bacteria, resulting in an increased resistance of the cells when they are subsequently exposed to X rays.
KeywordsPyrimidine Dimer Strand Exchange Dose Rate Effect Post Replication Repair Strain DM456
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- Leclerc, J. and Setlow, J. (1972). J. BacterioL 110, 930.Google Scholar
- Radman, M. (1974). In Molecular and Environmental Aspects of Mutagenesis (in press).Google Scholar
- Rupp, W. D. (1972). Biophys. Soc. Abstr. 12, 148a.Google Scholar
- Rupp, W. D., Zipser, E., vonEssen, C., Reno, D., Prosnitz, L. and Howard-Flanders, P. (1970). In Dose Rate Effects in Radiobiology as Applied to Radiotherapy p. 1. Brookhaven Nat. Lab. Publication No. 50203 (C-57).Google Scholar
- Zipser, E. (1973). Ph. D. Thesis, Yale University.Google Scholar