The Degradation of Duplex DNA by the recBC DNase of Escherichia coli
The catalytic reactions of the recBC enzyme of Escherichia coli with various substrates are reviewed, and a model for the sequence of events in the degradation of duplex DNA is presented. The potential of the enzyme to take part in genetic recombination and repair is discussed.
KeywordsGeneral Medical Science Duplex Molecule Interstrand Cross Exonuclease Reaction Neutral Sucrose Gradient
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